HPLC validation and stress degradation behavior of Etoricoxib in tablets dosage form
نویسندگان
چکیده
منابع مشابه
Determination of Risperidone and forced degradation behavior by HPLC in tablet dosage form
A simple, specific, sensitive, precise stability-indicating high-performance liquid chromatography method for determination of Risperidone in tablet dosage form was developed and validated. A Waters Xterra RP8 column (250*4.6 mm, 5 μ) in isocratic mode, with mobile phase consisting of a mixture of solution (10 mM potassium dihydrogen phosphate, pH 3.5 ± 0.05): acetonitrile: methanol (65:20:15) ...
متن کاملDevelopment and validation of RP-HPLC method for determination of content uniformity of rabeprazole sodium in its tablets dosage form
The aim of the present work was to develop simple, shorter and effective HPLC method with UV detection (285nm) and subsequent validation for the content uniformity determination of Rabeprazole Sodium in marketed tablet samples. The method uses isocratic mobile phase of 0.1M sodium phosphate buffer (pH adjusted to 6.5 with sodium hydroxide solution) and acetonitrile 65:35 compositions on reverse...
متن کاملDetermination of Ilaprazole and Domperidone in Individual Dosage form Tablets by RP-HPLC
Ilaprazole (Fig. 1) is a new proton-pump inhibitor not previously studied in human patients with ulcer disease. This study evaluated and compared it with a reference proton-pump inhibitor omeprazole in the treatment of gastric and duodenal ulcers. Proton-pump inhibitors have been used therapeutically for many years and show great efficacy in accelerating ulcer healing. Currently researches are ...
متن کاملHydrolytic Degradation Profile and RP-HPLC Estimation of Cilostazol in Tablet Dosage Form
A simple, selective, precise and stability-indicating high-performance liquid-chromatographic method of analysis of cilostazol in pharmaceutical dosage form was developed and validated. The solvent system consisted of 10 mM phosphate buffer (pH 6.0):acetonitrile:methanol (20:40:40). Retention time of cilostazol in C18 column was 5.7 +/- 0.1 min at the flow rate 1.3 ml/min. Cilostazol was detect...
متن کاملDevelopment and Validation of Reversed Phase Hplc Method for Estimation of Ceftriaxone in Pharmaceutical Dosage Form
Ceftriaxone sodium (Figure 1) is chemically (6R,7R)-7[[(2Z)-(2-amino-4thiazolyl)(methoxyimino)acetyl]amino]-8-oxo-3[[(1,2,5,6-tetrahydro-2-methyl-5,6-ioxo-1,2,4-triazin3-yl)thio]-methyl]-5-thia-1-azabicyclo[4.2.0]oct-2-ene2-carboxylic acid 1 . Ceftriaxone is a third generation, semisynthetic cephalosporin antibiotic. Cephalosporins are derivatives of 7aminocephalosporic acid and are closely rel...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Benha Journal of Applied Sciences
سال: 2023
ISSN: ['2356-976X', '2356-9751']
DOI: https://doi.org/10.21608/bjas.2023.199355.1113